Immune Response and Hypersensitivity

Axia College Material auxiliary C Immune Response and Hypersensitivity deflate Wound Multimedia Activity After completing the Puncture Wound Multimedia Activity, complete the table below. List the four features of the inflammatory response covered in the activity in the order of occurrence. Rewrite the events in your own words, using vocabulary terms from Ch. 2 of the text. Vascular Events in an Inflammatory Response Events Simplified description of event Professional description of event 1st Germs from the nail are introduced below the skin. The skin is broken in some way, in this typesetters case by a nail puncturing the skin. When this occurs, it allows the entry of pathogens (germs such as bacteria) into the wound. 2nd Surrounding cells leak wandering that affects the line of merchandise An immediate local innate response in the infected tissues vessels. is generated by components of the immune strategy which are present in those tissues.Those components of the immune system include macrophages (a type of white blood cell) and equilibrise proteins (proteins that are involved in the initial immune response). 3rd The fluid affecting the surrounding blood vessels causes Other immune cells (such as neutrophils), leave the the release of other cells into the tissue. circulation, attracted by the inflammatory mediators released by the mast cells and envision the wounded area. 4th As the wounded part of the body reacts to the germs, The neutrophil cells attack the pathogens that have entered authorized cells destroy these germs. the wound and begin to kill them.In the meantime, another specialized immune cell, known as the dendrite cell, carried separate of the dead pathogen back to the nearby lymphatic system. Hypersensitivity Give a brief description and example in your own words for each of the four types of hypersensitivity presented in Ch. 2. Hypersensitivity Matrix typeface of Hypersensitivity Description Exam ple Type I Allergic/Anaphylactic Anaphylaxisis an acuteAnaphylaxis is oftentimes triggered by substances that are injected or ingested and multi-system severe thereby gain access into the blood stream. An explosive reaction involving the skin, type I hypersensitivitylungs, nose, throat, and gastrointestinal tract commode then result. reaction. Type II Cytotoxic/Cytolytic Cytotoxic are caused byThe reaction of the antibody adhesion leads to the activation of complement antibodies, which proteins (again, encountered earlier). The complement proteins destroy the persons attach to a persons own blood cells.Type II reactions often occur in incompatible blood transfusions. own blood cells or tissue cells. Type lead Immune Complex Animmune complexis After anantigen-antibody reaction, the immune complexes can be subject to any(prenominal) of a formed from the number of responses, includingcomplementdeposition,opsonization,phagocytosis, or integral binding of an proce ssing byproteases. antibody to a soluble antigen. Type IV Cell-mediated/DelayedType IV (cell-mediated)Cell-mediated immunity is directed primarily at microbes that survive reactions appear 12-72 inphagocytesandmicrobesthat infect non-phagocytic cells. hours after exposure to an allergen.